5HTP Weight Loss information - Does this serotonin precursor help curb your appetite? Will you lose weight if you take this supplement? What is the right dosage to eat less? Should you take 50 mg, 100, 150 or 300 mg a day?
5HTP. or 5-HTP, is a supplement that converts in the brain into serotonin. Serotonin is an important neurotransmitter involved in mood, behavior, appetite, impulse control, and sleep. Scientists have examined the role of 5HTP in weight loss and appetite control. It does appear that many users who take this supplement notice that they have less appetite. The question that still remains to be answered is in regards to tolerance. Would the continued use of 5-HTP supplements over several weeks or months lead to tolerance or would the benefits of appetite suppression leading to weight loss continue? Also, is there a risk to using 5HTP pills for weight loss if done so for prolonged periods? It appears thus far that the use of this natural supplement for days or weeks is quite safe. Until more studies are published, it would be wise to not use these natural pills daily for longer than one or two months. You can take a week break each month to be on the safe side, and then resume again if no side effects or problems have occurred.
Benefits of Diet Rx with 5 HTP for weight loss
All natural appetite suppressant, decreases appetite so you eat less
Helps you maintain healthy cholesterol and lipid levels
Provides a variety of antioxidant from two dozen herbs and nutrients
Improves natural energy so you get motivated to take walks and burn more
calories
Balances mood so you don't have the urge to eat to satisfy a need for a mood
lift
Improves will power and choice of food selection
5-HTP and
appetite suppression leading to weight loss in rodents
5-Hydroxy-L-tryptophan 5 HTP suppresses food intake in food-deprived and
stressed rats.
Pharmacol Biochem Behav. 2004 January. Amer A, Breu J, McDermott J, Wurtman
RJ, Maher TJ. Amer A, Breu J, McDermott J, Wurtman RJ, Maher TJ. Department of
Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences,
Boston, MA, USA.
Giving L-tryptophan, serotonin's circulating precursor, or a serotonin-releasing
drug can decrease food intake and body weight. Giving 5-hydroxy-L-tryptophan
5-HTP, serotonin's immediate intracellular precursor, has been thought to be
ineffective in enhancing brain serotonin synthesis unless it is coadministered
with a dopa decarboxylase inhibitor to protect 5-HTP from destruction outside
the brain. We have examined the effect of 5-HTP on food consumption and tissue
5-HTP levels among rats subjected to two different hyperphagic stimuli, food
deprivation and a standardized stress (tail pinch), and on plasma 5-HTP levels
in humans. In rats, 5-HTP (3-200 mg/kg ip) suppressed food intake in a
dose-dependent manner in both models, but was at least eight times more
effective in our stress-hyperphagia model. This suppression was blocked by
coadministration of another large neutral amino acid (LNAA), L-valine. Brain
5-HTP levels correlated significantly with peak plasma 5-HTP or 5-HTP / LNAA
levels. Additionally, among humans, oral 5-HTP (1.2-2.0 mg/kg) produced, after 1
and 2 h, a significant increase in plasma 5-HTP (1.5- to 2.3-fold). These
observations suggest that 5-HTP may be useful in controlling the excessive food
intake sometimes generated by stress, even if given without decarboxylase
inhibitors or other drugs.
5HTP converts
into Serotonin which regulates appetite
5HTP is a natural
supplement that converts in the brain into serotonin. Serotonin is known
as 5-HT, or 5-hydroxytryptamine. It is found in many places in the body
particularly the brain, gastrointestinal system, and blood cells.
5-HTP and weight loss, suppression of appetite
A few studies with 5-htp
indicate that this supplement may be of benefit
in weight loss. 5HTP could be used
temporarily for weight loss while other lifestyle and dietary
changes are being incorporated regarding a life long plan for keeping
weight off. Not everyone has weight loss with
5HTP. A study in rodents indicates that 5HTP may be useful in controlling
the excessive food intake sometimes generated by stress. 5-HTP is found in
Diet Rx, a potent appetite suppressant.